Many of these have already been researched as applicant drugs, but They're opioids, belonging to a similar class of compounds as morphine and hydrocone.
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Conolidine is found in the bark from the tropical flowering shrub Tabernaemontana divaricata, typically called the pinwheel flower. The plant is indigenous to southeast Asia, exactly where it has extensive been used in common Chinese, Ayurvedic and Thai medicines to take care of fever and pain.
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